When couples are unable to conceive naturally, it means that despite regular and unprotected intercourse over a specified period, pregnancy has not occurred.
Infertility can be a challenging and emotionally taxing experience for individuals and couples. It is essential for those facing difficulties in conceiving to seek medical advice and explore potential treatments or interventions, such as assisted reproductive technologies like IVF.
After trying to conceive naturally for two years without success, my partner and I decided to explore IVF (In Vitro Fertilization). At the time, I knew very little about the process, so I began researching fertility centers and decided to schedule a consultation. Unfortunately, I wasn’t happy with my initial choice. The doctor I selected was often unavailable, and my only previous attempt at treatment—Intrauterine Insemination (IUI)—had not worked.
Understanding IUI
For those unfamiliar, IUI is a type of fertility treatment that involves placing sperm directly into a woman’s uterus during her ovulation period. This procedure aims to increase the number of sperm that reach the fallopian tubes, thereby enhancing the chances of fertilization. Here’s a quick overview of how it works:
1. Monitoring: The woman’s ovulation cycle is monitored using blood tests and ultrasounds.
2. Sperm Collection: Sperm from a partner or donor is collected and prepared in a lab to separate healthy sperm.
3. Insemination: During ovulation, the prepared sperm is introduced into the uterus using a thin catheter.
4. Aftercare: The woman may be advised to rest, but most can resume normal activities shortly after.
IUI is often recommended for couples facing mild male factor infertility, unexplained infertility, or certain conditions that prevent natural conception. It’s less invasive and generally less expensive than IVF.
Finding the Right Fertility Center
After my disappointing experience, I sought a different fertility center that prioritized patient care and had positive reviews. The fertility process is incredibly stressful, and I wanted a clinic that would understand that and help alleviate my concerns. I eventually found RMA (Reproductive Medicine Associates) and was pleased with my initial consultation. I decided to move forward with treatment.
Preparing for IVF
Before starting IVF, several tests are conducted to assess both partners' fertility and overall health. Common tests for women include:
1. Hormone Testing: Blood tests to check hormone levels, including FSH (Follicle-Stimulating Hormone), LH (Luteinizing Hormone), estradiol, and progesterone, which help evaluate ovarian function.
2. Ovarian Reserve Testing: Tests such as an ultrasound to assess the number of follicles and an AMH (Anti-Müllerian Hormone) blood test to estimate the number of viable eggs.
3. Hysterosalpingography (HSG): An X-ray procedure to check for blockages in the fallopian tubes and to evaluate the shape of the uterine cavity.
4. Transvaginal Ultrasound: An ultrasound to examine the ovaries and uterus for abnormalities, cysts, or fibroids.
5. Infectious Disease Screening: Testing for sexually transmitted infections (STIs) and other infectious diseases.
For Men:
1. Semen Analysis: A comprehensive evaluation of sperm count, motility (movement), morphology (shape), and overall sperm health.
2. Hormone Testing: Blood tests to check hormone levels that affect sperm production, such as testosterone and FSH.
3. Infectious Disease Screening: Similar to women, men may also be tested for STIs and other infections.
Additional Assessments:
- Genetic Testing: In some cases, genetic screening may be recommended to identify potential genetic disorders that could be passed on to offspring.
- Medical History Review: A thorough review of personal and family medical histories for any factors that could impact fertility.
These tests help fertility specialists develop a personalized IVF plan and identify any underlying issues affecting conception.
**Medications and Ovarian Stimulation**
I was prescribed several medications to stimulate ovarian function and prepare my body for IVF. Here’s a breakdown of common medications used and a picture of what i was prescribed:
Ovarian Stimulation Medications:
1. Gonadotropins: These are injectable medications that contain FSH (Follicle-Stimulating Hormone) and LH (Luteinizing Hormone). They stimulate the ovaries to produce multiple follicles (and thus eggs). Examples include:
- Follitropin alpha (Gonal-F)
- Follitropin beta (Follistim)
- Human Menopausal Gonadotropin (hMG, Menopur)
2. GnRH Agonists or Antagonists:
- GnRH Agonists: These may be used to prevent premature ovulation by suppressing the body’s natural hormone signals. They are often started at the beginning of the stimulation cycle. Example: Leuprolide.
- GnRH Antagonists: These are used later in the cycle to prevent premature ovulation. They are administered as injections. Example: Cetrotide or Ganirelix.
3. Trigger Shot:
- Once the follicles are adequately developed, a trigger shot of human chorionic gonadotropin (hCG) or a GnRH agonist is administered to induce final maturation of the eggs. Example: Ovidrel or Pregnyl.
4. Additional Medications:
- Estrogen and Progesterone: Depending on the individual’s treatment plan, estrogen may be administered during stimulation, and progesterone is typically started after egg retrieval to support the uterine lining for potential embryo transfer.
- Antibiotics: Sometimes prescribed to prevent infection during and after the egg retrieval procedure.
5. Pain Management:
- Some doctors may recommend medications for pain management or sedation during the egg retrieval process.
It's important for individuals undergoing IVF to closely follow their fertility specialist's instructions regarding medication dosages and timing, as these factors are crucial for the success of the procedure. Regular monitoring through ultrasounds and blood tests will help track the response to these medications and make necessary adjustments. The treatment will vary for different people.
Once the eggs have matured, the next step in the IVF process is egg retrieval, also known as oocyte retrieval. This procedure typically takes place about 34-36 hours after administering the trigger shot (hCG or GnRH agonist). Here’s an overview of what to expect during the egg retrieval process:
1. Preparation:
- Fasting: Patients may be instructed to fast for several hours before the procedure.
- Anesthesia: The procedure is usually performed under sedation or general anesthesia to minimize discomfort.
2. The Procedure:
- Ultrasound Guidance: The doctor uses a transvaginal ultrasound to visualize the ovaries and follicles containing the eggs.
- Needle Aspiration: A thin needle is guided through the vaginal wall and into each follicle to aspirate (suction out) the fluid containing the eggs. This is done carefully to avoid damaging surrounding tissues.
3. Duration:
- The egg retrieval procedure typically lasts about 20-30 minutes.
4. Post-Procedure Care:
- Recovery: After the procedure, patients are monitored in a recovery area until the effects of anesthesia wear off. They may experience some cramping or spotting, which is normal.
- Instructions: Patients will receive post-procedure care instructions, including activity restrictions and when to follow up with their healthcare provider. I felt completely fine after the egg retrievals. This is a picture of me getting ready for one of the egg retrievals.
5. Egg Assessment:
- The retrieved eggs are evaluated in the laboratory for quality and maturity. Only mature eggs will be used for fertilization.
6. Next Steps:
- After egg retrieval, the eggs are either fertilized with sperm (from a partner or a donor) through insemination or ICSI (Intracytoplasmic Sperm Injection). The resulting embryos are then cultured for several days before the best candidates are selected for transfer to the uterus.
Egg retrieval is a critical step in the IVF process, and while it may seem daunting, it is generally safe and well-tolerated by most patients.
In my first egg retrieval, I was fortunate to produce five eggs. Unfortunately, after fertilization, none of them developed into embryos by day 7, which meant there were no embryos available for transfer. While this was disappointing, I was optimistic about future attempts.
My insurance covered three egg retrievals, so I’ve begun preparing to embark on this process once again. I was hopeful that with each attempt, we can work towards a positive outcome.
I did my second egg retrieval, and I was excited that I produced eight eggs! This was a significant improvement compared to my first retrieval, where I only had five. Naturally, I felt a wave of happiness knowing that having more eggs increases our chances of getting a viable embryo.
Every step in this journey can feel like a mix of hope and anxiety, but this time, I felt more optimistic. The thought of having more eggs meant a greater possibility of successful fertilization and development. It’s amazing how each retrieval brings a new wave of emotions and anticipation. As I prepare for the next steps, I’m reminded of the importance of resilience and positivity in this process. Each attempt brings us closer to our goal, and this time was a success, we had one healthy embryo.
After the third egg retrieval, where I again produced eight eggs but none made it to the embryo stage, it became clear that the time had come to transfer our one healthy embryo. Ultimately, we had one healthy embryo to work with. While I wished for more embryos to increase our chances, I decided to proceed with the transfer. To stay calm and reduce stress, I decided to try fertility acupuncture, which I believe helped me immensely. I found a specialized clinic and attended sessions for four months leading up to the embryo transfer. If you're considering this, check with your insurance to see if they cover fertility acupuncture.
Preparing for embryo transfer is an important step in the IVF process, as it sets the stage for a successful implantation. Here are key preparations that typically take place before the embryo transfer:
7. Transfer Day Preparation:
- Fasting: Some clinics may advise fasting for a few hours before the transfer.
- Comfortable Clothing: Wearing comfortable clothing for the procedure can help ease any anxiety.
8. Emotional Preparation:
- Support System: Having a strong support system in place, whether from partners, family, or friends, can be beneficial emotionally.
- Counseling: Some individuals may find it helpful to speak with a counselor or therapist to navigate the emotional aspects of the IVF journey.
9. Transfer Procedure:
- Understanding the Procedure: Knowing what to expect during the embryo transfer can help alleviate anxiety. The procedure is typically quick and involves placing the embryos into the uterus using a thin catheter.
Overall, thorough preparation for embryo transfer can enhance the chances of successful implantation and ultimately lead to a positive outcome. Each step taken during this phase is important for creating the best environment for the embryos to thrive.
The Waiting Game
After my embryo transfer, I had to wait two weeks for a pregnancy test. My anxiety was overwhelming, and I couldn’t wait, so I took a home pregnancy test after seven days. It was positive! While I was thrilled, I worried it might be a false positive due to the hormones I was taking. I wouldn’t feel truly confident until I confirmed it with the fertility clinic.
When I finally received the official confirmation of my pregnancy, I felt incredibly lucky. It was nothing short of a miracle, especially knowing it was my only chance. I’m forever grateful to science for this opportunity, and I wish everyone could experience this kind of happiness.
Challenges Along the Way
However, my stress didn’t end there. At just two months pregnant, I contracted COVID-19 and experienced spotting and a high fever. I was devastated, knowing the risks of miscarriage in the first trimester. Finding a healthcare provider willing to see me during this time was challenging, further heightening my anxiety.
After quarantining for seven days, I was relieved to return to the office, and thankfully, everything was okay. Throughout my pregnancy, I continued attending maternity acupuncture, which provided relaxation and support.
Overall, my pregnancy was relatively smooth, aside from having placenta previa, which required a scheduled C-section at 37 weeks. Just a week before my 43rd birthday, my miracle baby girl was born.
That was my successful IVF journey, and I sincerely hope that all you mamas-to-be experience the same luck. I thank God every day for this miracle. If you have any questions about the process or need support, please don’t hesitate to reach out.
Also, don’t forget to check out our website, where you’ll find a wealth of resources on everything from pregnancy to postpartum, and raising newborns to toddlers. Your journey is unique, and I’m here to support you every step of the way!
With love and best wishes
Mommy, Me and Beyond Team